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THE PRACTICAL SIGNIFICANCE OF PRELIMINARY STUDY OF THE CHEMICAL SCALE, STRUCTURE AND STRENGTH OF URINARY STONES FOR CHOOSING A RATIONAL METHOD OF THEIR DESTRUCTION

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Abstract

Introduction. Urolithiasis is one of the oldest diseases known to medicine; however, the mechanisms of stone formation and development remain largely unclear. Physico-chemical, biological and biochemical processes that take place during the formation of urinary stones determine the peculiarities of their composition and structure, which is confirmed by modern methods of analysis: spectral, X-ray, polarization optical, immersion, infrared spectrometry, etc [1,2]. But it was determined that knowledge of the chemical composition and structure of urinary stones does not allow to improve their destruction. Urolithiasis, a complex multifactorial disease, results from an interaction between environmental and genetic factors. Epidemiological studies have shown that urolithiasis is associated with a number of lifestyle-related diseases, including cardiovascular disease, hypertension, chronic kidney disease, diabetes, and metabolic disorders. syndrome. Elucidation of the mechanisms underlying the formation of urinary stones will allow the development of new prophylactic agents [3,4]. For the development of new modern methods of mechanical destruction of urinary stones, data on the structure of urinary stones, which primarily determines their physical properties, are of particular importance. An example can be the fact that graphite and diamond have the same mineral composition (carbon), but the strength of each of them cannot be compared: one is fragile, the other is the hardest.


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Copyright (c) 2022 Konstantin Barannik , Robert Molchanov , Serhiy Barannik , Marharyta Kasparova