PROSPECTS FOR THE USE OF ERUCA SATIVA SEED OIL IN NORMALIZING THE SKIN MICROBIOTA IN PATIENTS WITH SCABIES
Abstract
Scabies (Sarcoptes scabiei var. hominis) is one of the most widespread neglected parasitic skin diseases worldwide. In addition to the direct damaging effects of the mite on the skin, the disease is associated with disruption of the epidermal barrier and a lterations in the composition of the skin microbiota. These changes promote the overgrowth of opportunistic pathogens such as Staphylococcus aureus and Streptococcus pyogenes, leading to secondary bacterial infections and enhanced inflammatory processes. T herefore, the search for natural topical agents capable of restoring the skin barrier, normalizing the skin microbiota, and reducing inflammation has become an important area of research. Objective. To evaluate the phytochemical composition of Eruca sativa (rocket) seed oil and scientifically substantiate its potential application as an adjunct topical agent in the комплекс treatment of scabies, particularly its possible effects on the skin microbiota and epidermal barrier. Results.Author Biography
Feruza Qalandarova
PhD Student
References
- Byrd A.L., Belkaid Y., Segre J.A. The human skin microbiome. Nature Reviews Microbiology. 2018;16(3):143– 155. DOI: 10.1038/nrmicro.2017.157.
- Bernigaud C., Zakrzewski M., Taylor S., et al.First Description of the Composition and the Functional Capabilities of the Skin Microbial Community Accompanying Severe Scabies Infestation in Humans. Microorganisms. 2021;9(5):907. DOI: 10.3390/microorganisms9050907.
- Bell L., Wagstaff C. Glucosinolates, Myrosinase Hydrolysis Products and Flavonols Found in Rocket (Eruca sativa). Journal of Agricultural and Food Chemistry. 2014.
- Khoobchandani M., Ojeswi B.K., Ganesh N., et al.Antimicrobial properties and analytical profile of traditional Eruca sativa seed oil. Food Chemistry. 2010;120(1):217–224.
- World Health Organization (WHO). Scabies. Fact Sheet. 2023.

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.